Hodgkin's disease primarily affects which system?

• A. Circulatory
• B. Lymphatic
• C. Nervous
• D. Digestive

Answer: (B)

Hodgkin's disease is a lymphoma that originates in the lymphatic system. The lymphatic system, including lymph nodes and related tissues, is where this cancer most commonly starts and spreads along the lymphatic pathways, reflecting its immune-system involvement. While the disease can later involve other organs, the primary system affected is the lymphatic system; the circulatory, nervous, and digestive systems are not the initial targets.