Hodgkin's disease primarily affects which bodily system?

• A. Digestive
• B. Lymphatic
• C. Nervous
• D. Muscular

Answer: (B)

Hodgkin's disease is a lymphoma that originates in lymphatic tissue, typically the lymph nodes, and spreads through the lymphatic system. The lymphatic system is part of the immune system and includes lymph nodes, spleen, thymus, and lymphatic vessels. Because the cancer arises from lymphocytes within this system, the primary bodily system affected is the lymphatic system, rather than the digestive, nervous, or muscular systems. It can involve other organs as it progresses—for example, the spleen or liver—but the hallmark initial involvement is lymphatic tissue.